The Regional Institute of Education Mysore ( Formerly Regional College of Education ) founded on 1st August, 1963, is one of five such institutions established by the National Council of Education Research and Training (NCERT), New Delhi. The other Institutes are located at Ajmer, Bhopal, Bhubaneswar and Shillong. The Regional Institutes were started with main the objective of qualitative improvement of school education through innovative pre-service and in-service teacher training programmes and relevant research, development and extension activities.

The Regional Institute of Education, Mysore has established itself as an institute of repute in the area of school and teacher education. The institute has endeavored to shoulder the  responsibilities and challenges generated by changes in the educational scenario of the country and the southern region. The Institute has been functioning as Regional Institute of Education since 1995, following a major shift in its focus from pre-service education to in-service education. The pre-service teacher education programmes of the institute are affiliated to the University of Mysore and cater to the needs of south indian states namely Andhra Pradesh, Karnataka, Kerala, Tamil Nadu, and Union Territories of Pondicherry and Lakshadweep.